A. Hughes, S. H. Hasan, G. W. Oertel, H. E. Voss, F. Bahner,'s Androgens II and Antiandrogens / Androgene II und PDF

By A. Hughes, S. H. Hasan, G. W. Oertel, H. E. Voss, F. Bahner, F. Neumann, H. Steinbeck, K.-J. Gräf, J. Brotherton, H. J. Horn, R. K. Wagner

ISBN-10: 364280859X

ISBN-13: 9783642808593

ISBN-10: 3642808611

ISBN-13: 9783642808616

Publication by means of Hartmann, Klaus

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ISMAIL et al. 2% for 64 replicates of 50 plasma and serum samples. For a fuller mathematical discussion of the concept of precision see papers such as that of EKINS and NEWMAN [18, 57]. 7. Sensitivity The sensitivity of the radioimmunoassay for androgens has been greater than that of competitive protein-binding. In our laboratories, the lowest quantity which can be measured by our radioimmunoassay is 15 pg, the standard curve at this level always giving a reading significantly different from that of 0 pg.

The basic idea is that the hormone modifies a protein (receptor~) so that it becomes capable of gene derepression, giving rise to RNA-synthesis with the subsequent protein and DNA synthesis. This is a very simplified version of what must be an extremely complicated process. Current theories revolve around the same theme, and a comparative evaluation will not be attempted here, since they have been extensively discussed by LIAO and FANG (1969), WILLIAMS-AsHMAN and REDDI (1971, 1972), BAXTER and TOMKINS (1971).

236, 1372-1379 (1961). : Spectral, chemical and template properties of mouse and rat uterine chromatin after in vivo administration of estradiol. Life Sci. 11, 753-762 (1972). : The inhibitory effect of anti-androgen (SH-714) on erythropoietic activity. Experientia (Basel) 25, 1104 (1969). : Rat-prostate cytology as a testis-hormone indicator and the prevention of castration changes by testis extract injection. Amer. J. Anat. 45,71-98 (1930). 1 4-3 ketosteroid 5a-oxidoreductase in the nuclear membrane of the rat ventral prostate.

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Androgens II and Antiandrogens / Androgene II und Antiandrogene by A. Hughes, S. H. Hasan, G. W. Oertel, H. E. Voss, F. Bahner, F. Neumann, H. Steinbeck, K.-J. Gräf, J. Brotherton, H. J. Horn, R. K. Wagner


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